Professor, Northwestern University Feinberg School of Medicine
Pathologist-in-Chief, Ann and Robert H. Lurie Children’s Hospital of Chicago
Dr. Perlman received her undergraduate education at Swarthmore College, followed by medical training and pathology residency at the Johns Hopkins Hospital, where she then served as the Division Head of Pediatric Pathology. She joined the Department of Pathology and Laboratory Medicine at the Ann & Robert H. Lurie Children’s Hospital of Chicago in 2002 where she is Pathologist-in-Chief. In addition to her administrative responsibilities, she serves as the Central Pathology Reviewer for the Renal Tumor Committee of the Children’s Oncology Group. In this role she evaluates approximately 600 new renal tumors registered within this group in North America each year. Dr. Perlman also heads a laboratory within the Lurie Children’s Research Center that investigates the molecular characteristics of pediatric renal tumors with the goal of impacting on their prognostic stratification and therapy. The Perlman laboratory has successfully utilized genomics in the classification of pediatric renal tumors, and in defining subsets of Wilms tumors. Dr. Perlman headed the TARGET collaboration with the NCI to fully characterize the genomics of high risk Wilms tumor, clear cell sarcoma of the kidney, and rhabdoid tumor, including global gene expression, copy number, and methylation analysis, and next generation sequencing.