Graduate student organizers
Guillermo Flores, Van Andel Institute Graduate School/Michigan State University Ph.D.-M.D. candidate
Guillermo is a fifth-year M.D.-Ph.D. student in the lab of Dr. Patrick Grohar. He is currently endeavoring to optimize a mithramycin-based therapy for the pediatric bone tumor Ewing sarcoma. Using biochemical assays as well as in vitro and in vivo models, Guillermo is seeking to understand the mechanism by which mithramycin inhibits the oncogenic driver of Ewing sarcoma. He is also working to understand the mechanism of off-target toxicity using cellular assays and developing new sequencing techniques. All this work is being done with the hope of providing patients with Ewing sarcoma a more effective and less toxic treatment. He is considering completing a residency in radiation oncology.
Leslie Wyman, Van Andel Institute Graduate School Ph.D. candidate
Leslie is a fourth-year graduate student at Van Andel Institute Graduate School, where she conducts Parkinson’s disease research in the laboratory of Dr. Darren Moore. She seeks to understand mechanisms of LRRK2 dimerization and activity in order to develop novel therapeutic strategies for LRRK2-induced neurotoxicity. She is excited about the opportunity to be involved in the organization of the 2019 Origins of Cancer and looks forward to gaining new knowledge outside her current field of research.
Scientific organizing committee